Characteristic Details
Active Ingredients Sildenafil 100mg, Tadalafil 20mg
Dosage Forms Tablet
Administration Oral
Prescription Status Prescription Only
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Available Dosage Forms and Strengths

Sildalis combines two potent agents: Sildenafil 100mg and Tadalafil 20mg. The formulation manifests in a singular dosage form — an oral tablet. The synergy between these active components aims to manage erectile dysfunction. Patients should adhere to prescribed dosages, mindful of individual health assessments and potential interactions.

The unique combination offers dual benefits. Sildenafil, well-known for its efficacy in a short window, works to provide immediate relief. Tadalafil extends the duration of therapeutic effects, enhancing the sexual experience. The dosing strategy balances rapid onset with prolonged action, suitable for those requiring flexible timing in intimate settings.

Mechanism of Action

Sildalis operates through dual mechanisms. Sildenafil 100mg inhibits phosphodiesterase type 5 (PDE5). This blockage amplifies the effect of nitric oxide by increasing cyclic GMP levels. The result is enhanced blood flow to the penile tissue, facilitating an erection upon sexual stimulation.

Simultaneously, Tadalafil 20mg maintains the vasodilatory effect over an extended period. By prolonging the half-life of the active compound, it allows for sustained readiness for sexual activity. This dual action capitalizes on the strengths of both agents, addressing both immediate and lasting needs.

Sildalis Contraindications

Sildalis is contraindicated in individuals with known hypersensitivity to Sildenafil, Tadalafil, or any excipients in the formulation. Patients with severe cardiovascular disorders should refrain from its use. These include individuals with recent myocardial infarction, severe arrhythmias, or significant hypotension.

Moreover, those concurrently using nitrates, or nitric oxide donors should avoid Sildalis. This combination can precipitate serious hypotensive episodes. Caution is advised in patients with renal or hepatic impairment, necessitating a thorough medical evaluation before initiation.

Sildalis Interactions

Sildalis may interact with numerous pharmaceuticals. Concomitant administration with nitrates poses significant risks, including life-threatening hypotension. Alpha-blockers used for hypertension can similarly exacerbate this effect.

Potent CYP3A4 inhibitors such as ketoconazole may elevate Sildenafil and Tadalafil plasma concentrations. The metabolism may slow down, heightening adverse effects. Conversely, CYP3A4 inducers may reduce efficacy. Patients must disclose all medications to their healthcare provider to avoid adverse outcomes.

Sildalis Signs and Symptoms of Overdose

Overdose of Sildalis could induce acute symptoms. These may encompass severe headache, prolonged erection, and sudden vision changes. Cardiovascular collapse is a rare but critical concern requiring immediate intervention.

Patients must seek medical help at the earliest sign of overdose. Supportive treatment focusing on symptomatic relief remains the mainstay. Dialysis does not expedite Sildenafil or Tadalafil clearance, underscoring the importance of prevention.

Sildalis Over The Counter

Sildalis is a prescription-only medication. Its use requires professional healthcare assessment. Over-the-counter options lack the dual action strength of Sildalis and may not provide the same therapeutic benefits.

Unsupervised use risks unintended interactions and adverse events. Patients should prioritize safety by consulting healthcare professionals. This ensures appropriate usage aligned with individual health profiles.

Ingredient Function
Sildenafil 100mg Enhances Blood Flow
Tadalafil 20mg Prolongs Effect

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